The already known therapeutic actions of CBD, the second major molecule present in cannabis.

Cannabis is used against pain, nausea and vomiting, to stimulate the appetite, but also as a bronchodilator in asthma, as an antispasmodic in Parkinson's disease and multiple sclerosis or as a vasodilator in glaucoma. CBD is also used to reduce epileptic seizures and is equally effective on rare and severe forms.

Active effects of Cannabis

Help to alleviate anxiety and stress

by regulating the production of serotonin and dopamine in the brain. Thus, it can promote pleasure and good mood, which has the direct consequence of calming stress and anxiety.

Helps calm pain and muscle spasms

by acting directly on cannabinoid receptors in the brain. Similar to neurotransmitters, when stimulated by taking cannabis, they produce a body response that calms pain and inflammation. So, you can use it to relieve muscle and joint pain as well as menstrual pain.

Help with sleep, smoking, skin problem

It can also help you fall asleep and thus improve your sleep.Non-addictive, it can reduce the urge to smoke by taking a few drops as needed. It will act in the same way as for stress and pain.Reduces nausea and skin problems.According to Dalhousie University in Canada, CBD is now believed to have a therapeutic and/or preventive action in the management of pain associated with osteoarthritis.

Active molecules in Cannabis

THC: The THC is the most known molecule of the cannabis. In the EU, it is accepted when it represents 0.3% or less of the product.

CBD: CBD, or cannabidol, is the second most present molecule in hemp. It is not psychotropic and has no proven harmful consequences according to the WHO.

CBN: CBN or cannbiniol is a slightly psychoactive cannabinoid. Created by the oxidation of THC by UV rays or oxygen, CBN has about 10% of the effects of THC. Few studies have been done on CBN compared to THC and CBD. However, the few studies that have been done prove the sedative effect of CBN. It is thus of a great help in case of insomnia.

CBG: CBG or Cannabigerol is a non-psychoactive cannabinoid, like CBD. It seems that CBG is the stem cell of CBD and THC. Present in small quantities in the different varieties of cannabis, its extraction is rather difficult.

The endocannabinoid system (ECS)

Still under study at the moment as there are so many discoveries about it, it plays a crucial role in maintaining the different balances of the body. Present mainly in the nervous system, it is also present in peripheral tissues such as skin, organs, muscles and bones.
The balance of the body, also called homeostasis, is the fact that the body will permanently try to regulate its pH, that is to say to maintain its acid-base balance by the means mainly of this endocannabinoid system. It will constantly call upon this system to secrete cells that will restore its homeostasis.

To summarize, it is a cellular communication system composed of: Receptors, CB1 and CB2, present on the surface of cells are locks.Ligands, are the keys allowing the receptors to provoke a specific signal that leads to an effect. For example pleasure, good mood, relaxation.Enzymes, are proteins that activate or accelerate this effect by chemical reaction. They act as regulators producing or reducing the number of molecules that produce an effect in the body.For example, pain is a response of the body to an imbalance, acne, anxiety or hunger also.The endocannabinoid system is therefore one of the most important and complex communication systems in the body. Its main function is to react to imbalances in the body in order to maintain its homeostasis.

The Entourage Effect

The whole is more than the sum of its parts.

We do not know who of Aristotle or Confucius pronounced this emblematic sentence. One thing is for sure, the creator did not have cannabis in mind when he uttered this sentence. The entourage effect is precisely the fact that the effect of cannabis is more effective when all its compounds are combined rather than taken separately or partially.

Other componants in Cannabis

Terpenes

The Cannabis Sativa L. plant is composed of about 140 terpenes. They constitute the aromas and odors of cannabis. Present in many plants, they serve to protect them from herbivores and to attract pollinators such as bees. They have virtues recognized since the antiquity in Chinese medicine as being an excellent antibacterial and antimicrobial.

Myrcene

Myrcene is the most common terpene in cannabis. It is responsible for the saying that eating mango before consuming cannabinoids would increase their effects.

Pinene

Pinene is responsible for pine and fir aromas. It is found in pine resins and lemon. It is known for its anti-inflammatory, expectorant, bronchodilator and local antiseptic properties.

Limonene

Limonene is one of two terpenes formed from pinene. It is very present in lemon varieties of cannabis such as Lemon Haze. It is also found in plants like citrus, juniper or peppermint. It facilitates the absorption of other terpenes by the skin and body tissues.

Caryophyllene

Caryophyllene is found in basil, cloves, cinnamon leaves and black pepper. It is responsible for spicy aromas. It is the only terpene with a proven interaction with the endocannabinoid system (ECS).

Linalool

Linalool is a terpene responsible for lavender and floral smells. It helps cannabinoids bring calm and relaxation. It is found in plants such as cinnamon, bay leaf and mint. Some studies tend to show that linalool strengthens the immune system and reduces lung inflammation.

Terpinolene

Terpinolene is responsible for woody aromas with floral notes. It is found naturally in rosemary and sage. It is known to promote sleep and anxiety. 

Camphene Camphene is found in rosemary, fir, lavender and sage. It gives off a woody, piney smell and is known for its antispasmodic and bronchodilator properties.

Humulene

Humulene is a terpene valued by beer lovers as it is found in hops. It is appreciated for its antibacterial and anti-inflammatory properties.

Sabinene

Sabinene, present in various plants such as holm oak, spruce, juniper and black pepper. Appreciated for its citrus smell, it has effective antiseptic and antioxidant properties.

Flavonoids

Flavonoids are plant pigments.
They give bright colors to flowers, fruits and vegetables in order to attract insects polinisateurs. They also protect them from UV rays and fungi.
Discovered by Albert Szent-Györgyi, Nobel Prize of medicine in 1937 with the discovery of the vitamin C, he had initially called them vitamin P because of their efficiencies to reduce the permeability of the blood vessels.

Their therapeutic properties: 
They have outstanding anti-inflammatory, immunostimulant, antioxidant, anticoagulant and antitumor qualities.
The latest studies prove that they prevent diabetes, improve cognition and therefore memory, reduce the appearance of hemorrhoids, reduce cardiovascular risks and are more effective than aspirin.
Cannaflavin flavonoids are unique to cannabis and give the flowers their brown hues. For varieties with purplish highlights like Blueberry, they are anthocyanins, purple pigments also known as tannins found in wine.
Cannaflavins B and C are also studied for their antifungal and anticancer potential.